Qlosi vs Vuity vs Vizz
Blog Entry - December 1, 2025
A Simple Guide to Today’s Presbyopia Eye Drops
If you’re over 40 and noticing you need to hold your phone farther away to read, you are not alone. This happens to everyone — it’s called presbyopia. Now, there are prescription eye drops that can help you see up close without constantly reaching for readers.
The three main options are:
- Vuity
- Qlosi
- Vizz
They all work by making the pupil smaller to sharpen near vision, but they differ in strength, duration, and how they are used. Here’s an easy guide to help you compare them.
🌟 Quick Comparison Table
| Feature | Vuity | Qlosi | Vizz |
|---|---|---|---|
| Active ingredient | Pilocarpine 1.25% | Pilocarpine 0.4% | Aceclidine 1.44% |
| How fast it works | ⭐ ~15 min | ⭐⭐ ~15–20 min | ⭐⭐ ~30 min |
| How long it lasts | ⭐⭐ ~6 hours | ⭐⭐ 6–8 hours (with 2 doses) | ⭐⭐⭐ Up to ~10 hours |
| Dosing | 1 drop once daily | 1 drop once or twice daily | 1 drop once daily |
| Peak effectiveness | Moderate | Moderate–Strong | Strongest of the three in published studies |
| Night-vision dimming | ⚠️ Yes | ⚠️ Yes | ⚠️ Yes |
| Learn more at: | https://www.vuity.com | https://www.qlosi.com | https://www.vizz.com |
⭐ = good
⭐⭐ = very good
⭐⭐⭐ = excellent
📘 The Three Drops Explained
👓 Vuity
What it is: The first FDA-approved eye drop for presbyopia.
How it works: Shrinks the pupil and slightly activates the eye’s focusing system (accommodation).
Typical benefit: Works in about 15 minutes; lasts around 6 hours.
More info:
https://www.vuity.com
Prescribing info: https://www.rxabbvie.com/pdf/vuity_pi.pdf
👓 Qlosi
What it is: A lower-dose pilocarpine option with flexible dosing.
How it works: Shrinks the pupil with a comfort-oriented formulation.
Typical benefit: Works in 15–20 minutes; lasts up to 8 hours if a second dose is used.
More info:
https://www.qlosi.com
Provider info: https://www.qlosiecp.com
👓 Vizz
What it is: A once-daily, pupil-selective presbyopia drop using aceclidine.
How it works: Creates a strong “pinhole effect” for near vision without significantly straining the eye’s focusing muscles.
Typical benefit: Improves near vision within ~30 minutes; many users maintain near-vision clarity for up to 10 hours based on published trial results.
More info:
https://www.vizz.com
https://www.vizz.com/prescribing-information
🧠 “Which one is the best?”
There are no direct head-to-head studies, so no drop can claim an official win. But based on each product’s published clinical data:
- Vuity – Good improvement, established track record, once daily.
- Qlosi – Similar improvement to Vuity, with flexible twice-daily dosing.
- Vizz – Across published studies, Vizz showed the highest proportion of patients with strong near-vision improvement and the longest duration of effect (often up to ~10 hours). This makes Vizz appealing for people who want one drop that lasts through most of the workday.
🌙 Side Effects
All three drops may cause:
- Mild headache
- Eye redness or irritation
- “Dim” vision in low light
- Temporary distance blur after instillation
These effects come from the pupil becoming smaller. Most side effects are mild and fade as the drop wears off.
👍 Simple Recommendations
- Choose Vuity if you want the original once-daily option.
- Choose Qlosi if you want flexible twice-a-day dosing and a familiar pilocarpine base.
- Choose Vizz if you want the strongest and longest-lasting near-vision improvement based on published clinical trial data.
📲 Want To Compare Them Yourself?
- Vuity: https://www.vuity.com
- Qlosi: https://www.qlosi.com
- Vizz: https://www.vizz.com
